Orel S G, Mendonca M H, Reynolds C, Schnall M D, Solin L J, Sullivan D C
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
Radiology. 1997 Feb;202(2):413-20. doi: 10.1148/radiology.202.2.9015067.
To investigate the ability of magnetic resonance (MR) imaging to depict ductal carcinoma in situ (DCIS).
Between January 1992 and April 1996, 330 women underwent MR imaging before excisional biopsy. Of these, 101 women had carcinoma, 19 of whom had DCIS. The MR imaging findings in the 19 women were reviewed.
Thirteen of 19 patients had pure DCIS. The mean lesion diameter was 10 mm (range, 2-22 mm). MR imaging enabled identification of DCIS in 10 (77%) of the 13 cases as ductal enhancement (n = 6), regional enhancement (n = 3), or a peripherally enhancing mass (n = 1). The three lesions not identified had a mean diameter of 3.7 mm. Six of 19 patients had both DCIS and an invasive cancer. In four of these patients, DCIS was identified only at MR imaging (mean diameter, 3 mm). In two of six patients, DCIS was not identified at MR imaging.
MR imaging can depict mammographically visible and occult foci of DCIS. Some small foci of DCIS detected at mammography and histologic examination, however, may be occult at MR imaging.
探讨磁共振(MR)成像显示导管原位癌(DCIS)的能力。
1992年1月至1996年4月期间,330名女性在切除活检前行MR成像检查。其中101名女性患有癌症,其中19名患有DCIS。回顾了这19名女性的MR成像结果。
19例患者中有13例为单纯DCIS。病变平均直径为10mm(范围2 - 22mm)。MR成像能够在13例中的10例(77%)中将DCIS识别为导管强化(n = 6)、区域强化(n = 3)或周边强化肿块(n = 1)。未被识别的3个病变平均直径为3.7mm。19例患者中有6例同时患有DCIS和浸润性癌。在其中4例患者中,DCIS仅在MR成像中被识别(平均直径3mm)。在6例患者中的2例中,MR成像未识别出DCIS。
MR成像能够显示乳腺X线摄影可见和隐匿的DCIS病灶。然而,一些在乳腺X线摄影和组织学检查中检测到的小DCIS病灶在MR成像中可能是隐匿的。