Eisen J L, Beer D A, Pato M T, Venditto T A, Rasmussen S A
Department of Psychiatry and Human Behavior, Brown University, Providence, R.I, USA.
Am J Psychiatry. 1997 Feb;154(2):271-3. doi: 10.1176/ajp.154.2.271.
The authors evaluated the frequency of DSM-III-R obsessive-compulsive disorder in patients with a primary diagnosis of schizophrenia or schizoaffective disorder.
Patients with schizophrenia (N = 52) or schizoaffective disorder (N = 25) were evaluated for the presence of obsessions and compulsions by means of the Structured Clinical Interview for DSM-III-R, the Yale-Brown Obsessive Compulsive Scale, chart review, and contact with the treating clinicians.
Six (7.8%) of the 77 patients met the DSM-III-R criteria for both obsessive-compulsive disorder and schizophrenia or schizoaffective disorder.
These findings suggest that obsessive-compulsive disorder occurs in a substantial percentage of patients with schizophrenia or schizoaffective disorder. The addition of medications targeted at obsessive-compulsive disorder may be beneficial to these patients but requires systematic evaluation.
作者评估了原发性诊断为精神分裂症或分裂情感性障碍患者中DSM-III-R强迫症的发生率。
采用DSM-III-R结构化临床访谈、耶鲁-布朗强迫症量表、病历审查以及与治疗临床医生沟通的方式，对52例精神分裂症患者和25例分裂情感性障碍患者进行强迫观念和强迫行为评估。
77例患者中有6例（7.8%）符合DSM-III-R强迫症及精神分裂症或分裂情感性障碍的标准。
这些发现表明，强迫症在相当比例的精神分裂症或分裂情感性障碍患者中存在。添加针对强迫症的药物可能对这些患者有益，但需要进行系统评估。
