Uçok A, Tükel R, Ozgen G, Saylan M, Uzuner G
Clinique de Psychiatrie de la Faculté Médecine d'Istanbul, Turquie.
Encephale. 2006 Jan-Feb;32(1 Pt 1):41-4. doi: 10.1016/s0013-7006(06)76135-8.
The objective is to study the comorbidity rate of obsessive compulsive disorder and obsessive compulsive symptoms in patients with schizophrenia and their relation with the course of this illness.
73 out-patients from Istanbul Medical Faculty Department of Psychiatry and 4th Unit of Bakirköy Mental Hospital who met the DSM III-R criteria for schizophrenia were recruited for this study. Other inclusion criteria were being out of acute exacerbation phase of schizophrenia. Yale-Brown Obsessive-Compulsive Scale, Yale Brown Obsessive Compulsive Symptom Screening Inventory were applied to patients.
Comorbidity rate of obsessive-compulsive disorder in patients with schizophrenia was 9.6%, and also obsessive compulsive symptoms were detected 31% of patients. Aggressive obsessions were seen most frequently. These symptoms were also reported more frequently in the patients whose Global Assessment of Functionality score was higher than 45 points. Suicide attempts in psychiatric history were significantly higher for patients with obsessive-compulsive symptoms.
Our findings indicate that obsessive-compulsive symptoms are seen more frequently than previously reported, and have no major effect upon the course of schizophrenia.
研究精神分裂症患者中强迫症及强迫症状的共病率及其与该疾病病程的关系。
招募了来自伊斯坦布尔医学院精神病学系及巴基尔柯伊精神病院第四病房的73名符合精神分裂症DSM III-R标准的门诊患者。其他纳入标准为处于精神分裂症非急性加重期。对患者应用耶鲁-布朗强迫量表、耶鲁布朗强迫症状筛查量表。
精神分裂症患者中强迫症的共病率为9.6%，且31%的患者检测到强迫症状。攻击性强迫观念最为常见。在功能总体评定得分高于45分的患者中，这些症状的报告也更为频繁。有强迫症状的患者精神病史中的自杀未遂情况显著更多。
我们的研究结果表明，强迫症状的出现比之前报道的更为频繁，且对精神分裂症的病程没有重大影响。
