Nettleman M D, Alsip J, Schrader M, Schulte M
Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA.
J Gen Intern Med. 1996 Dec;11(12):765-7. doi: 10.1007/BF02598997.
To identify determinants of mortality after hip fracture, we performed a multicenter, retrospective study of 390 Medicare beneficiaries. Independent predictors of 30-day mortality included a history of congestive heart failure (odds ratio [OR] 32; 95% confidence interval [CI] 5, 192), angina (OR 26; 95% CI 4, 184), or chronic pulmonary disease (OR 11; 95% CI 2, 62). Postoperative use of aspirin was associated with a reduced risk of mortality (OR 0.24; 95% CI 0.08, 0.70). Cardiovascular events were the presumed cause of 63% of in-hospital deaths. Aspirin may have significant potential to reduce mortality in this population and deserves further study.
为了确定髋部骨折后死亡率的决定因素，我们对390名医疗保险受益人进行了一项多中心回顾性研究。30天死亡率的独立预测因素包括充血性心力衰竭病史（比值比[OR]32；95%置信区间[CI]5，192）、心绞痛（OR 26；95%CI 4，184）或慢性肺病（OR 11；95%CI 2，62）。术后使用阿司匹林与降低死亡风险相关（OR 0.24；95%CI 0.08，0.70）。心血管事件被认为是63%的住院死亡原因。阿司匹林在该人群中可能具有显著的降低死亡率的潜力，值得进一步研究。
