DIR：一种与反向重复序列相关的新型DNA重排。
DIR: a novel DNA rearrangement associated with inverted repeats.
作者信息
Pinder D J, Blake C E, Leach D R
机构信息
Institute of Cell and Molecular Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JR, UK.
出版信息
Nucleic Acids Res. 1997 Feb 1;25(3):523-9. doi: 10.1093/nar/25.3.523.
Abstract
A novel DNA rearrangement has been characterised that is both a direct and inverted repeat. This rearrangement involves the 2-fold duplication of a plasmid sequence adjacent to the site of insertion of a long palindrome. The sequence of this rearrangement suggests that it has arisen by strand slippage from the leading to the lagging strand of the replication fork as a consequence of the presence of the long palindrome.
摘要
一种新型的DNA重排已被鉴定出来，它既是直接重复序列又是反向重复序列。这种重排涉及到与一个长回文序列插入位点相邻的质粒序列的两倍重复。这种重排的序列表明，由于长回文序列的存在，它是由复制叉的前导链到后随链的链滑动产生的。
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