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老年人对流感灭活疫苗体液免疫反应的特点

Characteristic of humoral response of elderly to inactivated influenza vaccine.

作者信息

Siennicka J

机构信息

Department of Virology, National Institute of Hygiene, Warsaw, Poland.

出版信息

Arch Immunol Ther Exp (Warsz). 1996;44(5-6):389-94.

PMID:9017157
Abstract

Eighty persons immunized with inactivated influenza vaccine in 1990-1991 epidemic season were examined. Serological tests: hemagglutination inhibition (HI), lectin neuraminidase (LN) and Western blot were performed with serum specimens taken before and 3-4 weeks after vaccination. Distribution of anti-influenza antibodies in the subclass was also examined. The results revealed humoral response to vaccine strains of influenza virus and also to strains caused infections in the past.

摘要

对1990 - 1991流行季节接种了灭活流感疫苗的80人进行了检查。血清学检测:采用接种疫苗前及接种后3 - 4周采集的血清标本进行血凝抑制试验(HI)、凝集素神经氨酸酶试验(LN)和蛋白质印迹法检测。还检测了亚类中抗流感抗体的分布情况。结果显示,机体对流感病毒疫苗株以及过去引起感染的毒株均产生了体液免疫反应。

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