Piasecki W, Salwiński L, Froncisz W
Department of Biophysics, Jagiellonian University, Cracow, Poland.
Biophys J. 1997 Feb;72(2 Pt 1):613-8. doi: 10.1016/s0006-3495(97)78699-5.
A new electrophoresis model of charged components in a spherical phospholipid vesicle is proposed. In the new model the effective local tangential electric field is a result of the uniform external electric field modified by the electric field of redistributed charges. The modification is calculated on the basis of the Gouy-Chapman surface potential theory. Numerical calculations of steady-state distribution of charged molecules and the transmembrane potential are performed. The results show significant difference from the old, simplified model that neglects modification of the external electric field caused by redistributed charges.
提出了一种球形磷脂囊泡中带电成分的新电泳模型。在新模型中,有效局部切向电场是由重新分布电荷的电场对均匀外部电场进行修正的结果。这种修正是基于古依-查普曼表面电势理论计算得出的。对带电分子的稳态分布和跨膜电势进行了数值计算。结果表明,与忽略重新分布电荷对外部电场修正的旧的简化模型有显著差异。