• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Antibodies against HIV-1 from phage display libraries: mapping of an immune response and progress towards antiviral immunotherapy.

作者信息

Parren P W, Burton D R

机构信息

Scripps Research Institute. Department of Immunology, La Jolla, Calif., USA.

出版信息

Chem Immunol. 1997;65:18-56. doi: 10.1159/000319346.

DOI:10.1159/000319346
PMID:9018871
Abstract
摘要

相似文献

1
Antibodies against HIV-1 from phage display libraries: mapping of an immune response and progress towards antiviral immunotherapy.来自噬菌体展示文库的抗HIV-1抗体：免疫反应图谱及抗病毒免疫治疗进展
Chem Immunol. 1997;65:18-56. doi: 10.1159/000319346.
2
Phage-displayed mimotopes recognizing a biologically active anti-HIV-1 gp120 murine monoclonal antibody.识别具有生物活性的抗HIV-1 gp120鼠单克隆抗体的噬菌体展示模拟表位。
J Acquir Immune Defic Syndr. 2002 Oct 1;31(2):147-53. doi: 10.1097/00126334-200210010-00004.
3
Antigen selection from an HIV-1 immune antibody library displayed on yeast yields many novel antibodies compared to selection from the same library displayed on phage.与从展示在噬菌体上的相同文库中进行筛选相比，从展示在酵母上的HIV-1免疫抗体文库中进行抗原筛选可产生许多新型抗体。
Protein Eng Des Sel. 2007 Feb;20(2):81-90. doi: 10.1093/protein/gzl057. Epub 2007 Jan 22.
4
Molecular characterization of the circulating anti-HIV-1 gp120-specific B cell repertoire using antibody phage display libraries generated from pre-selected HIV-1 gp120 binding PBLs.利用从预先筛选的HIV-1 gp120结合外周血淋巴细胞（PBLs）生成的抗体噬菌体展示文库，对循环抗HIV-1 gp120特异性B细胞库进行分子特征分析。
J Immunol Methods. 2005 Feb;297(1-2):187-201. doi: 10.1016/j.jim.2004.12.008. Epub 2005 Jan 27.
5
Anti-human immunodeficiency virus type 1 human monoclonal antibodies that bind discontinuous epitopes in the viral glycoproteins can identify mimotopes from recombinant phage peptide display libraries.能结合病毒糖蛋白中不连续表位的抗人免疫缺陷病毒1型人单克隆抗体可从重组噬菌体肽展示文库中鉴定模拟表位。
AIDS Res Hum Retroviruses. 1997 Dec 10;13(18):1549-59. doi: 10.1089/aid.1997.13.1549.
6
Phages and HIV-1: from display to interplay.噬菌体与人类免疫缺陷病毒1型：从展示到相互作用
Int J Mol Sci. 2012;13(4):4727-4794. doi: 10.3390/ijms13044727. Epub 2012 Apr 13.
7
Natural human antibodies retrieved by phage display libraries from healthy donors: polyreactivity and recognition of human immunodeficiency virus type 1gp120 epitopes.通过噬菌体展示文库从健康供体中获取的天然人类抗体：多反应性及对人类免疫缺陷病毒1型gp120表位的识别
Scand J Immunol. 1999 Sep;50(3):270-9. doi: 10.1046/j.1365-3083.1999.00516.x.
8
Cross-neutralizing anti-HIV-1 human single chain variable fragments(scFvs) against CD4 binding site and N332 glycan identified from a recombinant phage library.从重组噬菌体文库中筛选到的针对 HIV-1 病毒 CD4 结合位点和 N332 糖基化位点的具有中和活性的人源单链抗体可变区片段(scFvs)。
Sci Rep. 2017 Mar 23;7:45163. doi: 10.1038/srep45163.
9
HIV-1 V3 loop crown epitope-focused mimotope selection by patient serum from random phage display libraries: implications for the epitope structural features.利用随机噬菌体展示文库从患者血清中选择 HIV-1 V3 环冠表位模拟表位：对表位结构特征的影响。
Mol Immunol. 2013 Jun;54(2):148-56. doi: 10.1016/j.molimm.2012.11.016. Epub 2012 Dec 25.
10
Development of Broadly Neutralizing Antibodies and Their Mapping by Monomeric gp120 in Human Immunodeficiency Virus Type 1-Infected Humans and Simian-Human Immunodeficiency Virus SHIVSF162P3N-Infected Macaques.在人类免疫缺陷病毒1型感染的人类和猿猴-人类免疫缺陷病毒SHIVSF162P3N感染的猕猴中广泛中和抗体的产生及其通过单体gp120进行的定位
J Virol. 2016 Mar 28;90(8):4017-4031. doi: 10.1128/JVI.02898-15. Print 2016 Apr.

引用本文的文献

1
Antiviral neutralizing antibodies: from in vitro to in vivo activity.抗病毒中和抗体：从体外到体内活性。
Nat Rev Immunol. 2023 Nov;23(11):720-734. doi: 10.1038/s41577-023-00858-w. Epub 2023 Apr 17.
2
Phage proteins are expressed on the surface of Neisseria gonorrhoeae and are potential vaccine candidates.噬菌体蛋白表达在淋病奈瑟菌的表面，是潜在的疫苗候选物。
PLoS One. 2018 Aug 23;13(8):e0202437. doi: 10.1371/journal.pone.0202437. eCollection 2018.
3
Oral Immunization of Rabbits with S. enterica Typhimurium Expressing Neisseria gonorrhoeae Filamentous Phage Φ6 Induces Bactericidal Antibodies Against N. gonorrhoeae.
用表达淋病奈瑟菌丝状噬菌体Φ6的鼠伤寒沙门氏菌对家兔进行口服免疫可诱导产生针对淋病奈瑟菌的杀菌抗体。
Sci Rep. 2016 Mar 4;6:22549. doi: 10.1038/srep22549.
4
Autoantibodies induced by chimeric cytokine-HIV envelope glycoprotein immunogens.嵌合细胞因子-人类免疫缺陷病毒包膜糖蛋白免疫原诱导的自身抗体。
J Immunol. 2014 May 15;192(10):4628-35. doi: 10.4049/jimmunol.1303401. Epub 2014 Apr 11.
5
An HIV-1 envelope glycoprotein trimer with an embedded IL-21 domain activates human B cells.一种带有嵌入的 IL-21 结构域的 HIV-1 包膜糖蛋白三聚体激活了人类 B 细胞。
PLoS One. 2013 Jun 24;8(6):e67309. doi: 10.1371/journal.pone.0067309. Print 2013.
6
Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF) activity.具有强效固有粒细胞-巨噬细胞集落刺激因子（GM-CSF）活性的嵌合 HIV-1 包膜糖蛋白。
PLoS One. 2013;8(4):e60126. doi: 10.1371/journal.pone.0060126. Epub 2013 Apr 2.
7
Herpesviral Fcgamma receptors: culprits attenuating antiviral IgG?疱疹病毒Fcγ受体：削弱抗病毒IgG的罪魁祸首？
Int Immunopharmacol. 2004 Sep;4(9):1135-48. doi: 10.1016/j.intimp.2004.05.020.
8
Human antibodies against spores of the genus Bacillus: a model study for detection of and protection against anthrax and the bioterrorist threat.针对芽孢杆菌属孢子的人源抗体：炭疽检测与防护及生物恐怖主义威胁的模型研究
Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5241-6. doi: 10.1073/pnas.082121599.
9
Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.靶向人类免疫缺陷病毒1型糖蛋白gp41膜近端外部区域的广谱中和抗体。
J Virol. 2001 Nov;75(22):10892-905. doi: 10.1128/JVI.75.22.10892-10905.2001.
10
The antiviral activity of antibodies in vitro and in vivo.抗体在体外和体内的抗病毒活性。
Adv Immunol. 2001;77:195-262. doi: 10.1016/s0065-2776(01)77018-6.