Hospital F, Dillmann C, Melchinger A E
Station de Génétique Végétale, INRA/UPS/INA-PG, Ferme du Moulon, Gif sur Yvette, France.
Comput Appl Biosci. 1996 Dec;12(6):455-62. doi: 10.1093/bioinformatics/12.6.455.
This paper provides a general method to derive algebraic expressions of genotype frequencies for multiple loci under various mating systems, including random mating, back-crossing, selfing, and full-sib mating. For each mating system, general equations are presented. In the case of three loci, comprehensive tables provide recurrence equations for genotype frequencies under random or self mating, and expected genotype frequencies after two generations of full-sib mating. Our results should prove useful in genetic linkage analysis.
本文提供了一种通用方法，用于推导在各种交配系统下多个位点基因型频率的代数表达式，这些交配系统包括随机交配、回交、自交和全同胞交配。对于每种交配系统，都给出了通用方程。对于三个位点的情况，综合表格提供了随机交配或自交情况下基因型频率的递推方程，以及两代全同胞交配后的预期基因型频率。我们的结果应证明在遗传连锁分析中是有用的。
