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胃上皮发育异常和腺瘤:历史回顾与分级的组织学标准

Gastric epithelial dysplasia and adenoma: historical review and histological criteria for grading.

作者信息

Goldstein N S, Lewin K J

机构信息

Department of Pathology, William Beaumont Hospital, Royal Oak, MI 48073, USA.

出版信息

Hum Pathol. 1997 Feb;28(2):127-33. doi: 10.1016/s0046-8177(97)90095-2.

DOI:10.1016/s0046-8177(97)90095-2
PMID:9023391
Abstract

Gastric epithelial dysplasia (GED) hypothetically is a straight-forward concept: dysplastic epithelium replacing the normal gastric epithelium of the stomach. However, since its inception several decades ago, the term GED has become progressively complex and confusing because of differences in definitions and nomenclature that have been based on cytological, microscopic, endoscopic, or gross features. This has resulted in the terms "dysplasia," "adenoma," "flat adenoma," and "depressed adenoma." Some authors have also included reactive changes under the term "dysplasia."

摘要

胃上皮发育异常(GED)理论上是一个简单直接的概念:发育异常的上皮取代胃的正常胃上皮。然而,自几十年前这个术语出现以来,由于基于细胞学、显微镜检查、内镜检查或大体特征的定义和命名存在差异,“GED”一词变得越来越复杂和令人困惑。这导致了“发育异常”“腺瘤”“扁平腺瘤”和“凹陷性腺瘤”等术语的出现。一些作者还将反应性改变纳入“发育异常”这一术语中。

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