Koktysz R, Zieliński K W, Kulig A
Department of Clinical Pathomorphology; Military Medical School, Lódź.
Pol J Pathol. 1997;48(1):5-14.
One of the fundamental problems in the pathology of gastric epithelium is differentiation of reactive or regenerative proliferations, which are not precancerous from precancerous proliferations (i.e. dysplasia) and cancer. Diagnostic and interpretational difficulties, a need for a close cooperation between pathologists and clinicians and an attempt to more precisely assess gastric epithelial dysplasia prompted us to evaluate the usefulness of the current morphological criteria in the diagnosis and grading of gastric epithelial proliferations. The present study indicates that there are no sufficient grounds for grading of dysplasia, although the current morphological criteria permit establishment of a correct diagnosis. Therefore, the currently used three-grade classification of dysplasia may be successfully replaced with an easier two-grade classification or resigned totally.
胃上皮病理学的基本问题之一是区分反应性或再生性增生（它们并非癌前病变）与癌前增生（即发育异常）及癌症。诊断和解释上的困难、病理学家与临床医生密切合作的必要性以及更精确评估胃上皮发育异常的尝试，促使我们评估当前形态学标准在胃上皮增生诊断和分级中的实用性。本研究表明，尽管当前形态学标准能够做出正确诊断，但却没有足够依据对发育异常进行分级。因此，目前使用的发育异常三级分类法或许可成功地被更简便的二级分类法取代，或者完全摒弃。
