Wolfson C, Branley J, Gottlieb T
Concord Repatriation General Hospital, NSW, Australia.
J Antimicrob Chemother. 1996 Dec;38(6):963-8.
The in-vitro susceptibility of 10 isolates of Bartonella henselae was assessed using the Etest. The organisms, one reference human strain and nine feline isolates, were grown on chocolate agar and the Etests read at days 5, 8 and 11. Six antibiotics, erythromycin, azithromycin, doxycycline, ciprofloxacin, rifampicin and vancomycin were evaluated. The results correlated well with published results using agar dilution. The results confirmed the high in-vitro susceptibility of B. henselae to erythromycin, azithromycin, doxycycline and rifampicin and to a lesser extent ciprofloxacin. The majority of isolates were resistant to vancomycin. Although in-vitro results of B. henselae susceptibility testing may not necessarily correlate with clinical response, the Etest may be a simpler way for laboratories to monitor for the development of resistance particularly in the setting of relapsing infection.
使用Etest评估了10株汉赛巴尔通体分离株的体外药敏性。这些菌株，1株参考人源菌株和9株猫源分离株，在巧克力琼脂上培养，Etest在第5、8和11天读取结果。评估了六种抗生素，即红霉素、阿奇霉素、强力霉素、环丙沙星、利福平和万古霉素。结果与使用琼脂稀释法发表的结果相关性良好。结果证实汉赛巴尔通体对红霉素、阿奇霉素、强力霉素和利福平具有较高的体外药敏性，对环丙沙星的药敏性较低。大多数分离株对万古霉素耐药。虽然汉赛巴尔通体药敏试验的体外结果不一定与临床反应相关，但Etest可能是实验室监测耐药性发展的一种更简单的方法，特别是在复发性感染的情况下。
