使用定制设计的铂微线圈进行实验性非手术经宫颈绝育术。
Experimental nonsurgical transcervical sterilization with a custom-designed platinum microcoil.
作者信息
Post J H, Cardella J F, Wilson R P, Griffith J W, Fox P S, Waybill P N, Hills J R
机构信息
Department of Radiology, Pennsylvania State University Hospital, Hershey 17033, USA.
出版信息
J Vasc Interv Radiol. 1997 Jan-Feb;8(1 Pt 1):113-8. doi: 10.1016/s1051-0443(97)70525-6.
PURPOSE
Investigation of a technique for nonsurgical female sterilization.
MATERIALS AND METHODS
A custom designed platinum microcoil with Dacron fibers was placed unilaterally into a fallopian tube and uterine horn of 10 rabbits after transcervical selective tubal catheterization with use of fluoroscopic guidance. The contralateral uterus and fallopian tube served as controls. After the rabbits were bred, pregnancy was determined by palpation and confirmed at autopsy. Postmortem histopathologic evaluation of uteri and fallopian tubes was performed.
RESULTS
Nine of the 10 rabbits became pregnant. None of the animals had embryos on the microcoil side. Nine rabbits had a total of 45 embryos on the control side. One animal failed to become pregnant on either side. The microcoil remained in good position in all 10 rabbits. There was a microcoil-associated, mild inflammatory tissue response in the uteri and fallopian tubes.
CONCLUSION
A platinum occlusion microcoil placed in a utero-tubal location has potential as a means for nonsurgical female sterilization.
目的
研究一种非手术女性绝育技术。
材料与方法
在透视引导下经宫颈选择性输卵管插管后，将定制设计的带有涤纶纤维的铂微线圈单侧置入10只兔子的输卵管和子宫角。对侧子宫和输卵管作为对照。兔子交配后，通过触诊确定妊娠情况，并在尸检时予以证实。对子宫和输卵管进行死后组织病理学评估。
结果
10只兔子中有9只怀孕。微线圈侧的动物均未发现胚胎。9只兔子的对照侧共有45个胚胎。1只动物两侧均未怀孕。微线圈在所有10只兔子中均保持良好位置。子宫和输卵管出现了与微线圈相关的轻度炎症组织反应。
结论
置于子宫输卵管部位的铂封堵微线圈有潜力作为一种非手术女性绝育方法。
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