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[褪黑素对完整及去垂体大鼠的肾脏影响]

[The renal effects of melatonin in intact and epiphysectomized rats].

作者信息

Pishak V P, Kokoshchuk H I

出版信息

Fiziol Zh (1994). 1995 Sep-Dec;41(5-6):23-6.

PMID:9026387
Abstract

Epiphysectomy in adult pubescent Wistar rats causes polyuria and Na uresis at the expense of the increased rate of the glomerular filtration and sodium filtration charge. Melatonin in a dose of 4.31 mkM/100 g of the body weight increased the glomerular filtration of both sodium and water and stimulated the sodium tubular transport in rats with intact epiphysis and did not normalize changes of the nephron excretory activity after epiphysectomy.

摘要

对成年青春期Wistar大鼠进行骺板切除术会导致多尿和钠尿,代价是肾小球滤过率和钠滤过负荷增加。剂量为4.31 mkM/100 g体重的褪黑素增加了钠和水的肾小球滤过,并刺激了具有完整骨骺的大鼠的肾小管钠转运,但并未使骺板切除术后肾单位排泄活动的变化恢复正常。

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[The renal effects of melatonin in intact and epiphysectomized rats].[褪黑素对完整及去垂体大鼠的肾脏影响]
Fiziol Zh (1994). 1995 Sep-Dec;41(5-6):23-6.
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[Functional relations of the adrenal cortex, thyroid and pineal body. II. Adrenal cortex reaction following epiphysectomy and administration of melatonin].[肾上腺皮质、甲状腺和松果体的功能关系。II. 松果体切除及褪黑素给药后的肾上腺皮质反应]
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Pinealectomy-induced elevation of collagen content in the intact skin is suppressed by melatonin application.褪黑素的应用可抑制松果体切除引起的完整皮肤中胶原蛋白含量的升高。
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[The influence of epiphysectomy and melatonin on the antidepressive effect in disordered function of the beta-adrenergic mechanisms in rats].[骺板切除术和褪黑素对大鼠β-肾上腺素能机制功能紊乱中抗抑郁作用的影响]
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[The role of microsomal oxidation processes in the development of haloperidol tolerance during melatonin administration and epiphysectomy in rats].[微粒体氧化过程在褪黑素给药及大鼠松果体切除术中氟哌啶醇耐受性发展中的作用]
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