Kostenko V O
Fiziol Zh (1994). 1995 Sep-Dec;41(5-6):91-6.
Experimental study of white rats has shown that the intragastric introduction of sodium nitrate at a rate of 9.6 g/kg of their mass is followed by the development of considerable disturbances of energy metabolism in kidneys. It was shown that the depression and separation of oxidation and phosphorylation, decrease energetic potential in the kidney tissues. The results obtained permit supposing the significant role of nitric oxide in kidneys as a factor resulting in bioenergetic disturbances. Maximum maintenance of Fe-NO complexes was marked 24 hours after the introduction of sodium nitrate and it corresponded to maximum disturbances of energy metabolism.
对白鼠的实验研究表明，以每千克体重9.6克的剂量给白鼠灌胃硝酸钠后，其肾脏的能量代谢会出现相当大的紊乱。结果显示，氧化与磷酸化过程受到抑制和分离，肾脏组织中的能量潜力降低。所得结果表明，一氧化氮在肾脏中作为导致生物能量紊乱的一个因素具有重要作用。在引入硝酸钠24小时后，铁-一氧化氮复合物的维持量达到最大值，这与能量代谢的最大紊乱相对应。
