[Role of the dopaminergic structures of the kidney in the renal effects of euphyllin].

Reserpine and galoperidol are shown to exercise blocking effect with regard to the diuretic and saluretic action of the xanthine-euphylline. Galoperiod prevented an accretion of the total renal blood flow induced by euphylline. Preliminary introduction to rats of alpha-methyl-DOPA and 1-DOPA abolished the blocking action of reserpine on the renal effects of euphylline. The renal influence of euphylline is mediated through dopamine-ergic structures, which are non-identical to adrenostructures. Dopamine is not merely a precursor of norepinephrine and epinephrine, but performs functions of its own in the organism.