[伴有胸膜播散或恶性胸腔积液的原发性肺癌（T4期晚期肺癌）的手术评估]

[Assessment of surgery for primary lung cancer with dissemination or malignant effusion of pleura (T4 advanced lung cancer)].

作者信息

Hiyoshi H, Iwanami H, Narita K, Tachibana M, Sakonji M, Tsuboi E

机构信息

Tsuboi Hospital Jisankai Medical Institute, Koriyama, Japan.

出版信息

Kyobu Geka. 1997 Feb;50(2):120-2.

PMID:9028069

Abstract

Twenty-four cases of primary lung cancer with dissemination or malignant effusion of pleura detected preoperatively or intraoperatively were surgically treated at our hospital. Mean survival time (MST) and two-year survival rate (2 YSR) were analyzed on their resected cases and non-resected cases with similar lesion. MST and 2 YSR of 19 cases with lobectomy, 5 cases with pneumonectomy including pleuropneumonectomy and 15 cases with no surgical procedure were 2.77 +/- 0.60 years, 53.4%, 1.51 +/- 0.50 years, 26.7% and 0.99 +/- 0.15 years, 6.7%. MST and 2 YSR of 13 cases with lymph node dissection under R 1 and 6 cases over R 2 on lobectomy group were 1.99 +/- 0.38 years, 37.5% and 5.66 +/- 1.71 years, 66.7%. These findings suggested that lobectomy with lymph node dissection of R 2 over may be a beneficial treatment of lung cancer with dissemination or malignant effusion of pleura.

摘要

我院对24例术前或术中发现有播散或恶性胸腔积液的原发性肺癌患者进行了手术治疗。对其切除病例和有相似病变的未切除病例分析了平均生存时间（MST）和两年生存率（2YSR）。19例行肺叶切除术、5例行包括胸膜肺切除术的全肺切除术及15例未行手术治疗患者的MST和2YSR分别为2.77±0.60年、53.4%，1.51±0.50年、26.7%和0.99±0.15年、6.7%。肺叶切除组中13例R1下淋巴结清扫及6例R2以上淋巴结清扫患者的MST和2YSR分别为1.99±0.38年、37.5%和5.66±1.71年、66.7%。这些结果提示，R2以上淋巴结清扫的肺叶切除术可能是治疗有播散或恶性胸腔积液肺癌的一种有效方法。