Jacob M, George S, Pulimood S, Nathan N
Department of Dermatology, Christian Medical College and Hospital, Vellore, Tamil Nadu, South India.
Int J Lepr Other Mycobact Dis. 1996 Dec;64(4):392-5.
During a period of 9 years, four male patients with HIV and Hansen's disease were detected in Tamil Nadu, South India. The sequence as to which infection came first is not known. All had high-risk sexual behavior with commercial sex workers and a past history of genital ulcer disease. Their spectrum of leprosy was multibacillary. Patient no. 1 had pure neural leprosy of the lepromatous type, which is rare. He also had a single episode of type 1 reaction which did not require steroid therapy. Despite having taken inadequate treatment, patient no. 2 remained clinically and bacteriologically quiescent after 4 years of follow up. He had a low CD4 count of 330 cells/mm3. The third patient completed a full course of multibacillary multidrug therapy, and a year later is clinically and bacteriologically inactive. The fourth patient died of AIDS within 2 months of the dual diagnosis.
在9年的时间里，印度南部泰米尔纳德邦发现了4例感染艾滋病毒且患有汉森病的男性患者。尚不清楚哪种感染先发生。他们都与商业性工作者有高危性行为，且有生殖器溃疡病史。他们的麻风病类型为多菌型。1号患者患有罕见的瘤型纯神经麻风。他还曾有过一次1型反应，无需类固醇治疗。尽管治疗不充分，但2号患者在随访4年后临床和细菌学上仍处于静止状态。他的CD4细胞计数较低，为330个细胞/立方毫米。第三名患者完成了多菌型多药治疗的全部疗程，一年后临床和细菌学上均无活动迹象。第四名患者在双重诊断后的2个月内死于艾滋病。
