Henry F, Piérard-Franchimont C, Cauwenbergh G, Piérard G E
Belgian SSTC Research Unit, University of Liege, Belgium.
J Am Geriatr Soc. 1997 Feb;45(2):220-2. doi: 10.1111/j.1532-5415.1997.tb04512.x.
To evaluate the age effect on both the mechanical properties and wrinkling of facial skin. This topic has not previously been addressed in the literature.
A total of 180 white women aged 18 to 67 years participated in the study. Each of the 5 decades of age was represented by 30 subjects, with the exception of menopausal women aged 48 to 57 years who were allocated to two groups of 30 according to the use or non-use of hormone replacement therapy (HRT).
A University medical center, Belgian SSTC Research Unit 5596.
Mechanical properties of the skin were measured on the face using a computerized suction device. Skin contours were assessed using optical profilometry and computerized image analysis.
Skin aging of the face is characterized by a progressive increase in extensibility associated with a decreased elasticity. The loss of tonicity is accompanied by a progressive deepening of facial creases. HRT appears to limit the age-related rheological changes without showing a preventive effect on wrinkling of facial skin.
Aging of facial skin resembles, in some ways, the features previously reported on sun-protected areas of the forearms. HRT has a beneficial effect that may slow the overall process of aging without, however, limiting the number and depth of wrinkles.
评估年龄对面部皮肤力学性能和皱纹的影响。此前文献中尚未涉及该主题。
共有180名年龄在18至67岁之间的白人女性参与了该研究。除48至57岁的绝经女性根据是否使用激素替代疗法(HRT)分为两组各30人外,每个年龄段的5个十年均由30名受试者代表。
比利时SSTC研究单位5596的一所大学医学中心。
使用计算机化抽吸装置在面部测量皮肤的力学性能。使用光学轮廓测量法和计算机化图像分析评估皮肤轮廓。
面部皮肤老化的特征是延展性逐渐增加,弹性降低。张力丧失伴随着面部皱纹的逐渐加深。HRT似乎能限制与年龄相关的流变学变化,但对面部皮肤皱纹没有预防作用。
面部皮肤老化在某些方面类似于先前在前臂防晒区域报道的特征。HRT具有有益效果,可能会减缓整体老化过程,但不能减少皱纹的数量和深度。