Bequignon A, Moreau S, Goullet de Rugy M, Bourdon N, Babin E, Valdazo A
Service ORL, CHU, Caen.
Ann Otolaryngol Chir Cervicofac. 1996;113(4):233-6.
We report a case of Kikuchi's disease in a young man. It is a rare entity, described for the first time in 1972. It manifests clinically with cervical adenopathy and fever, often associated with other non-specific clinical signs. Laboratory tests are often normal. The diagnosis is established on the basis of histologic of lymph node excisional biopsy. Kikuchi's disease is likely to be misinterpreted as malignant lymphoma or systemic lupus erythematosus. It generally needs no treatment because it runs a spontaneously benign course with complete resolution of the symptoms within 6 months. Secondary systemic lupus erythematosus may develop. For this reason, regular follow-up of patients is recommended. The etiopathogenesis of this disease is still unknown, perhaps due to an immunologic phenomenon. It could be a hyperimmune reaction induced by various antigenic agents (infectious, neoplasic), or an autoimmune process.
我们报告一例年轻男性的菊池病。这是一种罕见的疾病，于1972年首次被描述。其临床症状表现为颈部淋巴结病和发热，常伴有其他非特异性临床体征。实验室检查通常正常。诊断基于淋巴结切除活检的组织学结果。菊池病很可能被误诊为恶性淋巴瘤或系统性红斑狼疮。它通常无需治疗，因为其病程呈自发良性，症状在6个月内可完全缓解。可能会继发系统性红斑狼疮。因此，建议对患者进行定期随访。这种疾病的病因仍不清楚，可能是一种免疫现象。它可能是由各种抗原性因素（感染性、肿瘤性）诱导的超免疫反应，或者是一个自身免疫过程。
