Ladagnous J F, Rousseau J M, Gaucher A, Saïssy J M, Pitti R
Service d'anesthésie-réanimation, HIA Legouest, Metz, France.
Ann Fr Anesth Reanim. 1996;15(5):677-80. doi: 10.1016/0750-7658(96)82135-6.
A 22-year-old man treated with ceftazidime-amikacine for a Pseudomonas aeruginosa pneumonia, experienced two days later allergic symptoms, acute renal failure and urinary sediment abnormalities. The renal biopsy showed an acute interstitial nephritis. Basophils stimulation test was positive for ceftazidime. Early diagnosis and discontinuation of the suspected agent is essential to allow rapid and complete recovery of renal function.
一名22岁男性因铜绿假单胞菌肺炎接受头孢他啶-阿米卡星治疗，两天后出现过敏症状、急性肾衰竭和尿沉渣异常。肾活检显示为急性间质性肾炎。嗜碱性粒细胞刺激试验对头孢他啶呈阳性。早期诊断并停用可疑药物对于肾功能迅速、完全恢复至关重要。
