Basu S, Majumdar J, Mitra R, Chowdhury J R
Department of Medical Oncology, Chittaranjan National Cancer Institute, Calcutta, India.
Surg Today. 1997;27(1):57-9. doi: 10.1007/BF01366940.
A 55-year old man with von Recklinghausen's disease was admitted to our hospital for investigation of weight loss, anorexia, and abdominal discomfort. Endoscopy findings revealed impairment in the extendability of the stomach by air, and barium meal studies showed a well-contracted stomach. On exploratory laparotomy, the whole of the stomach was found to be grossly shrunken with thickening of the walls suggesting a "linitis plastica" stomach. Histological findings confirmed stage III poorly differentiated diffuse infiltrative adenocarcinoma of the stomach. This report describes a rare case of "linitis plastica" stomach in a patient with peripheral neurofibromatosis (NF-1) indicating that the NF-1 disorder does not spare an individual from other common neoplastic disorders.
一名患有冯雷克林霍增氏病的55岁男性因体重减轻、厌食和腹部不适入院接受检查。内镜检查发现胃的充气扩张能力受损，钡餐造影显示胃明显收缩。在剖腹探查术中，发现整个胃严重萎缩，胃壁增厚，提示为“皮革胃”。组织学检查结果证实为胃III期低分化弥漫浸润性腺癌。本报告描述了一例罕见的外周神经纤维瘤病（NF-1）患者发生“皮革胃”的病例，表明NF-1疾病并不能使个体免于罹患其他常见的肿瘤性疾病。
