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神经纤维瘤病患者中的一种罕见恶性肿瘤:胃腺癌。

A rare malignancy in a patient with neurofibromatosis: gastric adenocarcinoma.

作者信息

Barut Bora, Ince Volkan, Ozdemir Fatih, Harputluoglu Murat, Isik Burak

机构信息

Department of General Surgery, Inonu University Faculty of Medicine, Malatya, Turkey.

Department of Gastroenterolgy, Inonu University Faculty of Medicine, Malatya, Turkey.

出版信息

North Clin Istanb. 2015 Sep 25;2(2):162-164. doi: 10.14744/nci.2015.33042. eCollection 2015.

Abstract

Neurofibromatosis is an autosomal dominant disease that is characterized by cutaneous hyperpigmentation and multiple neurofibromas and often accompanied by localized peripheral and central neural tumors. Gastrointestinal involvement is seen in 25% of the cases. Gastrointestinal stromal tumors, pancreatic and duodenal neuroendocrine tumors are the most common tumors in patients with neurofibromatosis. Neurofibromatosis and gastric adenocarcinoma constitute an extremely rare combination. In this case report we aim to present a patient with neurofibromatosis operated due to gastric adenocarcinoma.

摘要

神经纤维瘤病是一种常染色体显性疾病,其特征为皮肤色素沉着和多发性神经纤维瘤,常伴有局部周围和中枢神经肿瘤。25%的病例可见胃肠道受累。胃肠道间质瘤、胰腺和十二指肠神经内分泌肿瘤是神经纤维瘤病患者中最常见的肿瘤。神经纤维瘤病与胃腺癌构成一种极其罕见的组合。在本病例报告中,我们旨在介绍一名因胃腺癌接受手术的神经纤维瘤病患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d78f/5175097/f55a0a402302/NCI-2-162-g001.jpg

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