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[肌炎——克罗恩病的一种罕见并发症]

[Myositis--a rare complication of Crohn disease].

作者信息

Druschky A, Heckmann J, Engelhardt A

机构信息

Neurologische Klinik mit Poliklinik, Universität Erlange-Nürnberg.

出版信息

Fortschr Neurol Psychiatr. 1996 Oct;64(10):422-4. doi: 10.1055/s-2007-996586.

Abstract

Crohn's disease is a chronic relapsing inflammatory disorder primarily affecting the gastrointestinal system. Extraintestinal manifestations such as erythema nodosum, iridocyclitis, arthritis and sclerosing cholangitis are frequent. We report on a 57-year old male patient with the symptoms of Crohn's disease. Clinically he showed signs of a muscle disorder and muscle biopsy demonstrated a perimysial inflammation with lymphocytes and histiocytes. Complete remission was achieved by immunosuppressive treatment. Six cases presented in the literature are reviewed and the autoimmunological aspects of the pathogenesis discussed.

摘要

克罗恩病是一种主要影响胃肠系统的慢性复发性炎症性疾病。结节性红斑、虹膜睫状体炎、关节炎和硬化性胆管炎等肠外表现很常见。我们报告一例有克罗恩病症状的57岁男性患者。临床上他表现出肌肉疾病的体征,肌肉活检显示有淋巴细胞和组织细胞的肌束膜炎症。通过免疫抑制治疗实现了完全缓解。回顾了文献中报道的6例病例,并讨论了发病机制的自身免疫方面。

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