Druschky A, Heckmann J, Engelhardt A
Neurologische Klinik mit Poliklinik, Universität Erlange-Nürnberg.
Fortschr Neurol Psychiatr. 1996 Oct;64(10):422-4. doi: 10.1055/s-2007-996586.
Crohn's disease is a chronic relapsing inflammatory disorder primarily affecting the gastrointestinal system. Extraintestinal manifestations such as erythema nodosum, iridocyclitis, arthritis and sclerosing cholangitis are frequent. We report on a 57-year old male patient with the symptoms of Crohn's disease. Clinically he showed signs of a muscle disorder and muscle biopsy demonstrated a perimysial inflammation with lymphocytes and histiocytes. Complete remission was achieved by immunosuppressive treatment. Six cases presented in the literature are reviewed and the autoimmunological aspects of the pathogenesis discussed.
克罗恩病是一种主要影响胃肠系统的慢性复发性炎症性疾病。结节性红斑、虹膜睫状体炎、关节炎和硬化性胆管炎等肠外表现很常见。我们报告一例有克罗恩病症状的57岁男性患者。临床上他表现出肌肉疾病的体征，肌肉活检显示有淋巴细胞和组织细胞的肌束膜炎症。通过免疫抑制治疗实现了完全缓解。回顾了文献中报道的6例病例，并讨论了发病机制的自身免疫方面。
