沙土鼠单侧颈动脉闭塞后产生偏瘫的临界脑血流量。
Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil.
作者信息
Nakai K, Welch K M, Meyer J S
出版信息
J Neurol Neurosurg Psychiatry. 1977 Jun;40(6):595-9. doi: 10.1136/jnnp.40.6.595.
Abstract
Transient cerebral ischaemia, produced by temporary unilateral common carotid artery (CCA) occlusion, was studied in the gerbil by means of chronically implanted hydrogen electrodes. Unilateral CCA occlusion produced behavioural signs of neurological deficit only when regional cerebral blood flow values in the ipsilateral cerebral hemisphere fell below a critical range of 0.20-0.22 ml/gm brain/min. Postischaemic poor perfusion (no-reflow) was an infrequent observation after removal of CCA occlusion.
摘要
通过长期植入氢电极，在沙鼠身上研究了由单侧颈总动脉（CCA）临时闭塞所产生的短暂性脑缺血。仅当同侧脑半球的局部脑血流量值降至0.20 - 0.22毫升/克脑组织/分钟的临界范围以下时，单侧CCA闭塞才会产生神经功能缺损的行为体征。去除CCA闭塞后，缺血后灌注不良（无再流）是一种不常见的现象。
相似文献
1
Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil.沙土鼠单侧颈动脉闭塞后产生偏瘫的临界脑血流量。
J Neurol Neurosurg Psychiatry. 1977 Jun;40(6):595-9. doi: 10.1136/jnnp.40.6.595.
2
Regional cerebral ischemia in the gerbil: measurement of regional cerebral blood flow by quantitative autoradiography.
J Cereb Blood Flow Metab. 1986 Jun;6(3):348-57. doi: 10.1038/jcbfm.1986.59.
3
Cerebral ischemia-reperfusion injury in the gerbil.沙鼠脑缺血再灌注损伤
J Surg Res. 1987 May;42(5):462-6. doi: 10.1016/0022-4804(87)90019-9.
4
Controllable graded cerebral ischaemia in the gerbil: studies of cerebral blood flow and energy metabolism by hydrogen clearance and 31P NMR spectroscopy.沙鼠可控性分级脑缺血：通过氢清除法和31P核磁共振波谱法对脑血流和能量代谢的研究
NMR Biomed. 1993 May-Jun;6(3):181-6. doi: 10.1002/nbm.1940060303.
5
Delayed postischemic hypoperfusion: a potentially damaging consequence of stroke.缺血后延迟性低灌注：中风的一个潜在破坏性后果。
Neurology. 1979 Sep;29(9 Pt 1):1245-52. doi: 10.1212/wnl.29.9_part_1.1245.
6
Prediction of tolerance to carotid artery occlusion using transcranial Doppler ultrasound.使用经颅多普勒超声预测颈动脉闭塞耐受性
J Neurosurg. 1994 Jul;81(1):15-9. doi: 10.3171/jns.1994.81.1.0015.
7
The effects of unilateral carotid occlusion on the responses to decapitation in the gerbil brain.单侧颈动脉闭塞对沙鼠脑内断头反应的影响。
Brain Res. 1981 Feb 9;206(1):155-60. doi: 10.1016/0006-8993(81)90108-6.
8
Experimental model for repetitive ischemic attacks in the gerbil: the cumulative effect of repeated ischemic insults.沙鼠反复缺血性发作的实验模型：反复缺血性损伤的累积效应。
J Cereb Blood Flow Metab. 1987 Dec;7(6):773-82. doi: 10.1038/jcbfm.1987.133.
9
Autoradiographic analysis on second-messenger systems and local cerebral blood flow in ischemic gerbil brain.
J Cereb Blood Flow Metab. 1991 Mar;11(2):283-91. doi: 10.1038/jcbfm.1991.60.
10
New variability in cerebrovascular anatomy determines severity of hippocampal injury following forebrain ischemia in the Mongolian gerbil.脑血管解剖结构的新变异性决定了蒙古沙鼠前脑缺血后海马损伤的严重程度。
Brain Res. 2006 Feb 16;1073-1074:451-9. doi: 10.1016/j.brainres.2005.12.024. Epub 2006 Jan 26.
引用本文的文献
1
Common carotid artery stump pressure in the gerbil stroke model.沙鼠中风模型中的颈总动脉残端压力
J Neurol Neurosurg Psychiatry. 1984 Apr;47(4):365-71. doi: 10.1136/jnnp.47.4.365.
2
The vulnerability of gerbils to focal cerebral ischemia. Neurological signs and regional biochemical changes after ischemia and recirculation.沙鼠对局灶性脑缺血的易感性。缺血再灌注后的神经体征和局部生化变化。
Eur Arch Psychiatry Neurol Sci. 1988;238(1):11-8. doi: 10.1007/BF00381073.
3
Xanthine oxidase-derived hydrogen peroxide contributes to ischemia reperfusion-induced edema in gerbil brains.黄嘌呤氧化酶衍生的过氧化氢导致沙鼠脑缺血再灌注诱导的水肿。
J Clin Invest. 1988 May;81(5):1556-62. doi: 10.1172/JCI113488.
4
Metabolism of monoamine neurotransmitters in the evolution of infarction in ischemic striatum.缺血性纹状体梗死演变过程中单胺类神经递质的代谢
J Neural Transm. 1987;69(3-4):265-75. doi: 10.1007/BF01244347.
本文引用的文献
1
Effects of ischemia and other procedures on the brain and retina of the gerbil (Meriones unguiculatus).
Exp Neurol. 1966 Nov;16(3):255-62. doi: 10.1016/0014-4886(66)90062-8.
2
Cerebral ischemia in infant and adult gerbils. Relation to incomplete circle of Willis.
Arch Pathol. 1969 Mar;87(3):315-7.
3
Regional cerebral blood flow measured by intracarotid injection of hydrogen. Comparison of regional vasomotor capacitance from cerebral infarction versus compression.
Neurology. 1972 Jun;22(6):571-84. doi: 10.1212/wnl.22.6.571.
4
Communications between vertebro-basilar and carotid arterial circulations in the gerbil.沙鼠椎基底动脉与颈总动脉循环之间的交通支
Exp Neurol. 1974 Dec;45(3):503-8. doi: 10.1016/0014-4886(74)90155-1.
5
Cerebral edema following carotid artery ligation in the gerbil.沙鼠颈动脉结扎后的脑水肿
Arch Neurol. 1973 Jun;28(6):389-91. doi: 10.1001/archneur.1973.00490240049008.
6
The natural course of experimental cerebral infarction in the gerbil.
Neurology. 1972 May;22(5):510-5. doi: 10.1212/wnl.22.5.510.
7
Ischaemic brain damage in the gerbil in the absence of 'no-reflow'.沙鼠在无“无复流”情况下的缺血性脑损伤。
J Neurol Neurosurg Psychiatry. 1975 Dec;38(12):1197-1205. doi: 10.1136/jnnp.38.12.1197.
8
No-reflow phenomenon in the cerebral circulation of the gerbil.沙鼠脑循环中的无复流现象。
J Neurol Neurosurg Psychiatry. 1975 Dec;38(12):1190-3. doi: 10.1136/jnnp.38.12.1190.
9
Cerebral blood flow. A predictor of recovery from ischemia in the gerbil.
Arch Neurol. 1975 Jul;32(7):457-61. doi: 10.1001/archneur.1975.00490490061005.
10
A comparison of circling models for the detection of antiparkinson activity.用于检测抗帕金森活性的环行模型比较
Psychopharmacologia. 1975;41(1):57-64. doi: 10.1007/BF00421307.
Zotero 插件