沙土鼠单侧颈动脉闭塞后产生偏瘫的临界脑血流量。
Critical cerebral blood flow for production of hemiparesis after unilateral carotid occlusion in the gerbil.
作者信息
Nakai K, Welch K M, Meyer J S
出版信息
J Neurol Neurosurg Psychiatry. 1977 Jun;40(6):595-9. doi: 10.1136/jnnp.40.6.595.
Abstract
Transient cerebral ischaemia, produced by temporary unilateral common carotid artery (CCA) occlusion, was studied in the gerbil by means of chronically implanted hydrogen electrodes. Unilateral CCA occlusion produced behavioural signs of neurological deficit only when regional cerebral blood flow values in the ipsilateral cerebral hemisphere fell below a critical range of 0.20-0.22 ml/gm brain/min. Postischaemic poor perfusion (no-reflow) was an infrequent observation after removal of CCA occlusion.
摘要
通过长期植入氢电极，在沙鼠身上研究了由单侧颈总动脉（CCA）临时闭塞所产生的短暂性脑缺血。仅当同侧脑半球的局部脑血流量值降至0.20 - 0.22毫升/克脑组织/分钟的临界范围以下时，单侧CCA闭塞才会产生神经功能缺损的行为体征。去除CCA闭塞后，缺血后灌注不良（无再流）是一种不常见的现象。
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