Nahass G T
Department of Dermatology, St. Louis University Health Sciences Center, MO 63104, USA.
J Am Acad Dermatol. 1997 Feb;36(2 Pt 1):149-68; quiz 169-72. doi: 10.1016/s0190-9622(97)70274-3.
The antiphospholipid antibody syndrome is a multiple-system disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia, or recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with this disorder. Cutaneous manifestations are common and may be the presenting sign of the underlying disease. This article reviews the clinical manifestations, laboratory assays, histopathologic features, and treatment of the antiphospholipid antibody syndrome.
抗磷脂抗体综合征是一种多系统疾病，其特征为抗磷脂抗体持续升高和/或动脉或静脉血栓形成、血小板减少或反复自然流产。抗心磷脂抗体和狼疮抗凝物是与该疾病相关的不同类型的抗磷脂抗体。皮肤表现很常见，可能是潜在疾病的首发症状。本文综述了抗磷脂抗体综合征的临床表现、实验室检测、组织病理学特征及治疗方法。
