Ohtsuka T
Department of Dermatology, Hanyu Hospital, Japan.
Br J Dermatol. 1997 Jan;136(1):94-6.
It is unknown whether primary Sjögren's syndrome (pSS) and systemic lupus erythematosus (SLE) have the same nailfold capillary abnormality, although they show similarity in several clinical, immunological and genetic aspects. Microscopy of the nailfold capillaries was undertaken in the two diseases and the observed parameters were compared with age- and sex-matched controls using analysis of variance. pSS and SLE showed a different frequency in their clinical and laboratory findings, except for the presence of anti-SS-A/B antibodies. All nailfold capillary parameters showed significantly higher values than those of corresponding normal controls, although between pSS and SLE there was no significant difference. The results may indicate that pSS and SLE are part of a spectrum of disorder.
原发性干燥综合征（pSS）和系统性红斑狼疮（SLE）是否具有相同的甲襞毛细血管异常尚不清楚，尽管它们在临床、免疫和遗传等几个方面表现出相似性。对这两种疾病进行了甲襞毛细血管显微镜检查，并使用方差分析将观察到的参数与年龄和性别匹配的对照组进行比较。除了抗SS - A/B抗体的存在外，pSS和SLE在临床和实验室检查结果方面显示出不同的频率。所有甲襞毛细血管参数均显示出明显高于相应正常对照组的值，尽管pSS和SLE之间没有显著差异。结果可能表明pSS和SLE是一系列疾病的一部分。
