Pap L, Sárközy P, Farkas R, Bleicher E, Szegö A
Chinoin Pharmaceutical an Chemical Works Co. Ltd., AgChem BU, Budapest, Hungary.
Parasitol Res. 1997;83(2):203-5. doi: 10.1007/s004360050233.
An in vitro immersion bioassay was used to compare the efficacy of selected pyrethroids against a deltamethrin-resistant strain of rabbit ear mite (Psoroptes cuniculi). A lack of cross-resistance between bromo (deltamethrin) and chloro analogues (cypermethrin) of alpha-cyano-3-phenoxybenzyl-dihalovinyl-dimethylcyclopropane carboxylate was detected. Whereas deltamethrin proved to be inactive (48-h mortality 21.9% at 1000 mg/kg), each cypermethrin isomer mixture tested, including alpha-cypermethrin [IR(cis) alpha S + 1 S (cis) alpha R] and theta-cypermethrin [1R(trans) alpha S + 1 S (trans) alpha R] and their mixture at a ratio of 4/6, beta-cypermethrin, showed high efficiency (48-h mortality > or = 95% at 1000 mg/kg).
采用体外浸泡生物测定法比较了所选拟除虫菊酯对兔耳螨（兔痒螨）溴氰菊酯抗性品系的效果。检测到α-氰基-3-苯氧基苄基-二卤代乙烯基-二甲基环丙烷羧酸酯的溴代（溴氰菊酯）和氯代类似物（氯氰菊酯）之间不存在交叉抗性。虽然溴氰菊酯被证明无活性（在1000mg/kg时48小时死亡率为21.9%），但所测试的每种氯氰菊酯异构体混合物，包括α-氯氰菊酯[IR（顺式）αS + 1S（顺式）αR]和θ-氯氰菊酯[1R（反式）αS + 1S（反式）αR]及其4/6比例的混合物、β-氯氰菊酯，均显示出高效（在1000mg/kg时48小时死亡率≥95%）。
