Kolev O I, Möller C, Nilsson G, Tibbling L
Department of Otorhinolaryngology, University Hospital, Linköping, Sweden.
Can J Neurol Sci. 1997 Feb;24(1):53-7. doi: 10.1017/s0317167100021090.
Observation of physiological changes during motion sickness is required to quantify the degree of sickness. The review of the literature does not show unifying results. An objective symptom of motion sickness is facial pallor. It reflects changes in skin microcirculation which have not been measured so far.
Eleven healthy volunteers susceptible to motion sickness were subjected to eccentric vertical axis rotation. The dynamics and the correspondence of the changes in skin blood flow in two segments, forehead and finger, were measured by laser Doppler flowmeter.
The difference in the microcirculatory skin blood flow across the phases of motion sickness is significant for the forehead but not for the fingertip: the established dynamics of the forehead blood flow during motion sickness will be of benefit in quantifying the degree of sickness; there is no correlation between the blood flow changes in both measured areas; the rhythmic blood flow fluctuation increases during motion sickness; there is a difference between the blood flow responses to vestibular stimulation before the appearance of motion sickness and in the course of the sickness. Laser Doppler flowmetry is a reliable method in quantifying the degree of motion sickness.
为了量化晕动病的严重程度，需要观察晕动病期间的生理变化。文献综述并未显示出统一的结果。晕动病的一个客观症状是面色苍白。它反映了迄今为止尚未测量的皮肤微循环变化。
11名易患晕动病的健康志愿者接受偏心垂直轴旋转。用激光多普勒血流仪测量前额和手指两个部位皮肤血流变化的动态情况及相关性。
晕动病各阶段皮肤微循环血流在前额有显著差异，而在指尖无显著差异：所确定的晕动病期间前额血流动态变化有助于量化晕动病的严重程度；两个测量部位的血流变化之间无相关性；晕动病期间有节奏的血流波动增加；晕动病出现之前和患病过程中对前庭刺激的血流反应存在差异。激光多普勒血流测量法是量化晕动病严重程度的可靠方法。
