Cicerone K D, Smith L C, Ellmo W, Mangel H R, Nelson P, Chase R F, Kalmar K
JFK-Johnson Rehabilitation Institute, Edison, New Jersey, USA.
Brain Inj. 1996 Apr;10(4):277-86. doi: 10.1080/026990596124458.
A significant minority of patients who have sustained a mild traumatic brain injury (MTBI) may exhibit persistent disability. There have been few attempts to describe and evaluate the effectiveness of neurorehabilitation for these patients. We conducted a retrospective analysis of the results of a neuropsychological rehabilitation programme for 20 patients with MTBI. Based upon the ability to resume productive functioning after treatment, 10 patients were determined to exhibit a good outcome and 10 patients were considered to exhibit a poor outcome. Patients with good outcome exhibited significant pre-post-treatment improvements on both neuropsychological measures of cognitive functioning and self-reported post-concussive symptoms. Patients with poor outcome demonstrated little improvement in either area, and in some cases showed a decline in functioning. The results are consistent with the view that there may be significant variability in recovery and response to treatment after MTBI. There is a continued need to identify which patients may benefit from neurorehabilitation, develop specially tailored interventions, and conduct controlled, prospective studies in this area.
相当一部分轻度创伤性脑损伤（MTBI）患者可能会出现持续性残疾。很少有人尝试描述和评估针对这些患者的神经康复效果。我们对20名MTBI患者的神经心理康复项目结果进行了回顾性分析。根据治疗后恢复有效功能的能力，确定10名患者预后良好，10名患者预后较差。预后良好的患者在认知功能的神经心理测量和自我报告的脑震荡后症状方面，治疗前后均有显著改善。预后较差的患者在这两个方面几乎没有改善，在某些情况下功能还出现了下降。这些结果与以下观点一致，即MTBI后恢复和对治疗的反应可能存在显著差异。持续需要确定哪些患者可能从神经康复中受益，制定专门定制的干预措施，并在该领域进行对照的前瞻性研究。
