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Molecular cloning and expression of a novel Staphylococcus aureus antigen.

作者信息

Rieneck K, Renneberg J, Diamant M, Gutschik E, Bendtzen K

机构信息

Institute for Inflammation Research, Laboratory of Medical Immunology, TA 7544, Rigshospitalet, Copenhagen, N. Denmark.

出版信息

Biochim Biophys Acta. 1997 Feb 7;1350(2):128-32. doi: 10.1016/s0167-4781(96)00216-3.

Abstract

A novel gene encoding an antigen from Staphylococcus aureus was isolated from an expression library by screening with antisera from patients with deep Staphylococcus aureus infections. In one positive clone an open reading frame, named ORF-2, was identified. Recombinant ORF-2 protein reacted with human immune serum. ORF-2 was shown to be present in other Staphylococcus aureus strains, but not in related species.

摘要

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