Rho GTP酶与白细胞细胞骨架调节
Rho GTPases and leukocyte cytoskeletal regulation.
作者信息
Dharmawardhane S, Bokoch G M
机构信息
Department of Immunology, Scripps Research Institute, La Jolla, CA 92037, USA.
出版信息
Curr Opin Hematol. 1997 Jan;4(1):12-8. doi: 10.1097/00062752-199704010-00003.
Abstract
The Rho GTPases (Rho, Rac, and Cdc42) regulate assembly of the actin cytoskeleton in many cells, including leukocytes. Recent work in identifying the protein targets of these GTPases is providing greater insight into the mechanisms used by cells to control cytoskeletal dynamics for a variety of purposes.
摘要
Rho 鸟苷三磷酸酶（Rho、Rac 和 Cdc42）在包括白细胞在内的许多细胞中调节肌动蛋白细胞骨架的组装。最近在确定这些鸟苷三磷酸酶的蛋白质靶点方面的研究，正让人们更深入地了解细胞为实现各种目的而控制细胞骨架动力学所采用的机制。
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