Barondes S H, Alberts B M, Andreasen N C, Bargmann C, Benes F, Goldman-Rakic P, Gottesman I, Heinemann S F, Jones E G, Kirschner M, Lewis D, Raff M, Roses A, Rubenstein J, Snyder S, Watson S J, Weinberger D R, Yolken R H
Department of Psychiatry, Center for Neurobiology and Psychiatry, University of California, San Francisco 94143-0984, USA.
Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1612-4. doi: 10.1073/pnas.94.5.1612.
On November 29-30, 1995, the National Academy of Sciences and the Institute of Medicine brought together experts in schizophrenia and specialists in other areas of the biological sciences in a workshop aimed at promoting the application of the latest biological information to this clinical problem. The workshop paid particular attention to evidence of pathology in the brains of people with schizophrenia, and to the possibility that this reflects an abnormality in brain development that eventually leads to the appearance of symptoms. The participants were impressed with the complexity of the problem, and felt that multiple approaches would be required to understand this disease. They recommended that a major focus should be on the search for predisposing genes, but that there should be parallel research in many other areas.
1995年11月29日至30日,美国国家科学院和医学研究所召集了精神分裂症专家以及生物科学其他领域的专家,举办了一次研讨会,旨在推动将最新的生物学信息应用于这一临床问题。该研讨会特别关注精神分裂症患者大脑中的病理学证据,以及这是否反映了大脑发育异常并最终导致症状出现的可能性。参与者对该问题的复杂性印象深刻,并认为需要多种方法来理解这种疾病。他们建议主要重点应放在寻找易感基因上,但在许多其他领域也应开展平行研究。