Splinter W M, Komocar L
Department of Anaesthesia, Children's Hospital of Eastern Ontario, Ottawa, Canada.
Anesth Analg. 1997 Mar;84(3):506-8. doi: 10.1097/00000539-199703000-00007.
The effect of nitrous oxide on postoperative vomiting was evaluated in 330 children who underwent outpatient dental restorations. There were two groups in this single-blind, randomized, controlled study. One group received nitrous oxide during their anesthetic, while the non-nitrous oxide group did not receive nitrous oxide at any time. Anesthesia was induced by inhalation with halothane or with propofol intravenously. The incidence of vomiting for 24 h after surgery was recorded. Overall, the incidence of vomiting was similar, with 30% of the control patients and 35% of the nitrous-treated patients vomiting after their anesthetic. However, in-hospital vomiting was less in the control group: 15% vs 24%, control versus nitrous oxide, P = 0.03. In conclusion, nitrous oxide does not alter postoperative vomiting after halothane anaesthesia for dental restorations in children.
在330名接受门诊牙齿修复的儿童中评估了一氧化二氮对术后呕吐的影响。在这项单盲、随机对照研究中分为两组。一组在麻醉期间接受一氧化二氮，而无一氧化二氮组在任何时候都不接受一氧化二氮。通过吸入氟烷或静脉注射丙泊酚诱导麻醉。记录术后24小时的呕吐发生率。总体而言，呕吐发生率相似，对照组30%的患者和一氧化二氮治疗组35%的患者在麻醉后出现呕吐。然而，对照组的院内呕吐较少：对照组为15%，一氧化二氮组为24%，P = 0.03。总之，对于儿童牙齿修复的氟烷麻醉，一氧化二氮不会改变术后呕吐情况。
