el-Damarawy H, el-Sahwi S, Toppozada M
Prostaglandins. 1977 Sep;14(3):583-90. doi: 10.1016/0090-6980(77)90273-8.
Termination of pregnancy in missed abortion and intra-uterine fetal death was accomplished using vaginal suppositories of 20 mg PGE2 in 31 cases and the results were compared with oxytocin induction (with or without estrogen pre-treatment) in 17 cases at the doses routinely used in our hospital. The PG suppositories proved much more superior (96.7%) than oxytocin (47.7%), but induced a higher rate of side effects. The latter were not serious and were generally tolerated by the patients. There was a positive correlation between duration of fetal retention in utero and the induction expulsion time. The over all patient acceptance of the method was quite favourable and the approach appears to be a definite advance towards management of these cases.
对31例稽留流产和宫内死胎患者使用20毫克前列腺素E2阴道栓剂终止妊娠,并将结果与我院常规剂量下17例使用催产素引产(无论是否进行雌激素预处理)的患者进行比较。结果表明,前列腺素栓剂(成功率96.7%)比催产素(成功率47.7%)优越得多,但副作用发生率更高。不过这些副作用并不严重,患者一般能够耐受。胎儿宫内滞留时间与引产排出时间呈正相关。总体而言,患者对该方法的接受度相当高,这种方法似乎是处理这些病例的一个明确进展。