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内脏利什曼病中红细胞的脂质过氧化作用

Lipid peroxidation of erythrocytes in visceral leishmaniasis.

作者信息

Biswas T, Ghosh D K, Mukherjee N, Ghosal J

机构信息

Department of Physiology, Indian Institute of Chemical Biology, Jadavpur, Calcutta, India.

出版信息

J Parasitol. 1997 Feb;83(1):151-2.

PMID:9057713
Abstract

Lipid peroxidation of erythrocytes was studied in kala-azar patients having a considerable degree of anemia. Enhanced formation of oxidative metabolic products was observed in the erythrocytes of these patients. Decreased activities of the protective enzymes suggest impairment of the defense mechanism against peroxidative threat. These may contribute to some extent to the shortened lifespan of red cells in visceral leishmaniasis.

摘要

对患有相当程度贫血的黑热病患者的红细胞脂质过氧化进行了研究。在这些患者的红细胞中观察到氧化代谢产物的形成增加。保护酶活性降低表明对抗过氧化威胁的防御机制受损。这些可能在一定程度上导致内脏利什曼病中红细胞寿命缩短。

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