Kanfer E J, Nicol B A
Department of Haematology, Charing Cross and Westminster Medical School, Charing Cross Hospital, London, England.
J R Soc Med. 1997 Jan;90(1):16-8. doi: 10.1177/014107689709000106.
The erythrocyte sedimentation rate (ESR) remains a commonly measured indicator of disease, but is subject to several non-disease influences. The haemoglobin concentration (Hb) and ESR were measured in 1249 consecutive patients (492 men, 757 women) from primary care practices. An inverse correlation was found between Hb and ESR throughout the range of measured Hb, and in particular there was a significant difference in the median ESR of patients in the highest and lowest quartile for non-anaemic Hb (P < 0.001). These results indicate that correct clinical analysis of an ESR result should take into account the Hb, both in anaemic and in non-anaemic patients. Interpretative difficulties due to external influences on the measured ESR could be resolved by replacement of this test with plasma viscosity estimation.
红细胞沉降率(ESR)仍然是一种常用的疾病测量指标,但会受到多种非疾病因素的影响。对来自基层医疗诊所的1249例连续患者(492名男性,757名女性)测量了血红蛋白浓度(Hb)和ESR。在整个测量的Hb范围内,发现Hb与ESR呈负相关,特别是非贫血Hb最高和最低四分位数患者的ESR中位数存在显著差异(P<0.001)。这些结果表明,对ESR结果进行正确的临床分析时,无论是贫血患者还是非贫血患者,都应考虑Hb。由于外部因素对测量的ESR产生的解释困难,可以通过用血浆粘度估计替代该测试来解决。