孕期的红细胞沉降率及铁状态

ESR and iron status in pregnancy.

作者信息

Madan N, Kapoor S, Rusia U, Sharma S, Nayyar V L, Sundaram K R, Sood S K

机构信息

Department of Pathology, University College of Medical Sciences, Shahdara, Delhi.

出版信息

Indian J Pathol Microbiol. 1997 Oct;40(4):521-5.

PMID:9444865

Abstract

ESR (Westergen) correlated significantly with the iron status (as measured by Hb concentration, haematocrit, red cell count, MCH, P/H ratio, serum iron, TIBC and percent saturation of transferrin) in a group of pregnant women (PW) at term. Serum ferritin correlated negatively with the ESR but the correlation was not statistically significant. Serum ferritin levels of < 50 micrograms/L were present in 9 (34.6%) PW with ESR > or = 50 mm 1st hour and 5 (19.2%) PW with ESR < 50 mm 1st hour. The mean ESR in PW was 55.7 (+/- 22.9) and was > or = 50 mm 1st hour in 50% and < 75 mm 1st hour in 82.7%. The difference in the mean ESR in anaemic and nonanaemic PW was highly significant (p < 0.001), 87.5% anaemic PW with serum ferritin > 50 micrograms/L had ESR > or = 50 mm 1st hour, suggesting the possible effect of chronic infection in raising ferritin levels in these PW.

摘要

在一组足月孕妇中，红细胞沉降率（魏氏法）与铁状态（通过血红蛋白浓度、血细胞比容、红细胞计数、平均红细胞血红蛋白含量、P/H比值、血清铁、总铁结合力和转铁蛋白饱和度测定）显著相关。血清铁蛋白与红细胞沉降率呈负相关，但该相关性无统计学意义。红细胞沉降率≥50mm/第1小时的孕妇中有9例（34.6%）血清铁蛋白水平＜50μg/L，红细胞沉降率＜50mm/第1小时的孕妇中有5例（19.2%）血清铁蛋白水平＜50μg/L。孕妇的平均红细胞沉降率为55.7（±22.9），50%的孕妇红细胞沉降率≥50mm/第1小时，82.7%的孕妇红细胞沉降率＜75mm/第1小时。贫血孕妇和非贫血孕妇的平均红细胞沉降率差异极显著（p＜0.001），血清铁蛋白＞50μg/L的贫血孕妇中87.5%的红细胞沉降率≥50mm/第1小时，提示慢性感染可能对这些孕妇的铁蛋白水平升高有影响。