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均匀心房组织再入性易损性的一维建模。

One-dimensional modelling of the vulnerability to re-entry of homogeneous atrial tissue.

作者信息

Zhang H, Holden A V

机构信息

Department of Physiology, The University, Leeds.

出版信息

J Theor Biol. 1997 Jan 21;184(2):117-22. doi: 10.1006/jtbi.1996.0280.

DOI:10.1006/jtbi.1996.0280
PMID:9059591
Abstract

A one-dimensional excitable medium model of atrial tissue derived from the Earm-Hilgemann-Noble excitation equations for atrial excitation is used to investigate (1) the rate dependence of the conduction velocity of travelling wave solutions and (2) vulnerability to unidirectional conduction block and hence re-entry. The effects of changes in the ACh activated K+ current and Na+/K+ pump inhibition on these properties are computed.

摘要

一个基于用于心房兴奋的厄姆-希尔格曼-诺布尔兴奋方程推导得出的心房组织一维可兴奋介质模型,被用于研究:(1)行波解传导速度的频率依赖性;(2)对单向传导阻滞进而对折返的易感性。计算了乙酰胆碱激活的钾电流变化和钠钾泵抑制对这些特性的影响。

相似文献

1
One-dimensional modelling of the vulnerability to re-entry of homogeneous atrial tissue.均匀心房组织再入性易损性的一维建模。
J Theor Biol. 1997 Jan 21;184(2):117-22. doi: 10.1006/jtbi.1996.0280.
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Characteristics of atrial re-entry and meander computed from a model of a rabbit single atrial cell.从兔单个心房细胞模型计算得出的心房折返和曲折的特征。
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