Zhang H, Holden A V
Department of Physiology, The University, Leeds.
J Theor Biol. 1997 Jan 21;184(2):117-22. doi: 10.1006/jtbi.1996.0280.
A one-dimensional excitable medium model of atrial tissue derived from the Earm-Hilgemann-Noble excitation equations for atrial excitation is used to investigate (1) the rate dependence of the conduction velocity of travelling wave solutions and (2) vulnerability to unidirectional conduction block and hence re-entry. The effects of changes in the ACh activated K+ current and Na+/K+ pump inhibition on these properties are computed.
一个基于用于心房兴奋的厄姆-希尔格曼-诺布尔兴奋方程推导得出的心房组织一维可兴奋介质模型,被用于研究:(1)行波解传导速度的频率依赖性;(2)对单向传导阻滞进而对折返的易感性。计算了乙酰胆碱激活的钾电流变化和钠钾泵抑制对这些特性的影响。