用减毒剂量的布鲁氏菌 melitensis 菌株 Rev.1 对成年绵羊进行疫苗接种：安全性和血清学反应。
Vaccination of adult sheep with reduced doses of Brucella melitensis strain Rev.1: Safety and serological responses.
作者信息
Crowther R W, Orphanides A, Polydorou K
出版信息
Trop Anim Health Prod. 1977 May;9(2):85-91. doi: 10.1007/BF02236385.
PMID:906093
Abstract
A trial was made to test the safety of a Brucella melitensis strain Rev. 1 vaccine when used in various doses on pregnant sheep and a control group of pregnant goats. It was found that local sheep were more susceptible than goats to the effects of this vaccine, and that the accepted dosage rate of 10+5 viable organisms, as recommended for adult goats, should not be used on pregnant sheep.
摘要
进行了一项试验，以测试布鲁氏菌Melitensis Rev. 1菌株疫苗在不同剂量下用于怀孕绵羊和怀孕山羊对照组时的安全性。结果发现，本地绵羊比山羊对这种疫苗的影响更敏感，并且对于怀孕绵羊不应使用推荐给成年山羊的10 + 5活生物体的公认剂量率。
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