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Neurotransmitter-neuroendocrine responses to experimentally induced aggression in humans: influence of personality variable.

作者信息

Gerra G, Zaimovic A, Avanzini P, Chittolini B, Giucastro G, Caccavari R, Palladino M, Maestri D, Monica C, Delsignore R, Brambilla F

机构信息

Centro Studi Farmacotossicodipendenze, Ser. L, Az, U.S.L., Parma, Italy.

出版信息

Psychiatry Res. 1997 Jan 15;66(1):33-43. doi: 10.1016/s0165-1781(96)02965-4.

DOI:10.1016/s0165-1781(96)02965-4
PMID:9061802
Abstract

Aggressiveness was experimentally induced in 30 psychophysically healthy male subjects, 18-19 years old, divided into 15 cases with low normal and 15 with high normal basal aggressivity. Plasma norepinephrine (NE), epinephrine (EPI), growth hormone (GH), prolactin (PRL), cortisol (CORT) and testosterone (Te) concentrations were measured in basal conditions and during experimentally induced aggressiveness. Basal Te and stimulated NE, GH and Cort levels were higher in subjects with high-normal than in those with low-normal aggressiveness, suggesting that the functional tonus of the NE system and of the NE-dependent hormonal axes might be a modulator of the behavioral parameter.

摘要

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