Deboer T, Tobler I
Institute of Pharmacology, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.
Pflugers Arch. 1997 Jan;433(3):230-7. doi: 10.1007/s004240050272.
The electroencephalogram, electromyogram and cortical temperature (TCRT) were recorded in seven Djungarian hamsters adapted to a short photoperiod at 16 degrees C ambient temperature (TA; SP16). A baseline day was followed by 4 h sleep deprivation (SD) and 20 h recovery. The analysis included data obtained in earlier experiments at 22 degrees C TA in a long (LP22) and short photoperiod (SP22). In all three conditions the changes in TCRT during vigilance state episodes were a function of episode duration and, for waking and non-rapid eye movement (NREM) sleep, of TCRT at episode onset. The increase in TCRT during REM sleep became progressively larger from LP22 to SP22 to SP16. After SD the mean TCRT decreased below baseline in the LP22 and stayed above baseline in the SP22. This difference in the effect of SD on TCRT was reflected in its increase during REM sleep, which was attenuated during recovery in LP22, but was enhanced in SP22. The time course of TCRT during NREM sleep or waking episodes was unaffected by SD. Therefore, the overall difference in TCRT between baseline and recovery in the LP22 and SP22 is due to changes in the increase in TCRT during REM sleep.
在7只适应短光照周期、环境温度（TA）为16℃（SP16）的黑线仓鼠中记录了脑电图、肌电图和皮质温度（TCRT）。在基线日之后进行4小时睡眠剥夺（SD），然后进行20小时恢复。分析包括在早期实验中于22℃TA的长光照周期（LP22）和短光照周期（SP22）下获得的数据。在所有三种条件下，警觉状态发作期间TCRT的变化是发作持续时间的函数，对于清醒和非快速眼动（NREM）睡眠而言，是发作开始时TCRT的函数。从LP22到SP22再到SP16，快速眼动睡眠期间TCRT的增加逐渐变大。睡眠剥夺后，LP22中TCRT的平均值降至基线以下，而SP22中则保持在基线以上。睡眠剥夺对TCRT的这种影响差异反映在快速眼动睡眠期间其增加上，在LP22的恢复过程中这种增加减弱，但在SP22中增强。NREM睡眠或清醒发作期间TCRT的时间进程不受睡眠剥夺的影响。因此，LP22和SP22中基线与恢复之间TCRT的总体差异是由于快速眼动睡眠期间TCRT增加的变化所致。
