Ferraina S, Johnson P B, Garasto M R, Battaglia-Mayer A, Ercolani L, Bianchi L, Lacquaniti F, Caminiti R
Istituto di Fisiologia umana, Università di Roma La Sapienza, Italy.
J Neurophysiol. 1997 Feb;77(2):1034-8. doi: 10.1152/jn.1997.77.2.1034.
The role of area 7 m has been studied by recording the activity of single neurons of monkeys trained to fixate and reach toward peripheral targets. The target was randomly selected from eight possible locations on a virtual circle, of radius 30 degrees visual angle from a central target. Three tasks were employed to dissociate hand- from eye-related contributions. In the first task, animals looked and reached to the peripheral target. In a second task, the animal reached to the peripheral target while maintaining fixation on the central target. In the third task, the monkey maintained fixation on peripheral targets that were spatially coincident with those of the reaching tasks. The results show that cell activity in area 7 m relates, for some cells to eye position, for others to hand position and movement, and for the majority of cells to a combination of visuomanual and oculomotor information. This area, therefore, seems to perform an early combination of information in the processing leading from target localization to movement generation.
通过记录经训练可注视并伸向周边目标的猴子单个神经元的活动，对7m区的作用进行了研究。目标从距中央目标视角半径为30度的虚拟圆上的八个可能位置中随机选取。采用了三项任务来区分与手相关和与眼相关的作用。在第一项任务中，动物注视并伸向周边目标。在第二项任务中，动物在保持注视中央目标的同时伸向周边目标。在第三项任务中，猴子注视与伸手任务中的目标在空间上重合的周边目标。结果表明，7m区的细胞活动，对一些细胞而言与眼的位置有关，对另一些细胞而言与手的位置和运动有关，而对大多数细胞而言与视觉手动和动眼神经信息的组合有关。因此，该区域似乎在从目标定位到运动产生的处理过程中对信息进行早期整合。
