Schlierf G
Z Gesamte Inn Med. 1977 May 1;32(9):137-9.
The therapy of hyperlipidaemias is based on the realisation of few principles of nutrition. Reduction of the weight and energy-controlled permanent nutrition, respectively, has in a distinctly marked degree influence on the majority of the hypertriglyceridaemias. Also mixed hyperlipidaemias as well as hypercholesterolaemias if associated with overweight, show a good reactivity to calorie-restricted forms of diet. Increased bodily motion, also negativation of the energy balance by influencing the consumption of calories is also an excellent measure for the quick decrease of the triglyceride levels. Specific mechanisms increasing the triglyceride concentration can be excluded by a restriction of the sugar and alcohol consumption. Primary hyercholesterolaemias in normal body-weight can be influenced by a decrease and/or changing of the fat consumption in the sense wanted. Since there have been possible comparable decreases of the cholesterol level by forms of diet of different fat content, when the relation of repeatedly unsaturated to saturated fatty acids furthermore exists, here is the possibility for the adaptation to individual habits of nutrition. However, own investigations allow the conclusion that the total addition of fat should lie below 35 kcal %. Whether the coronary risk can be diminished by a nutrition decreasing lipids, was investigated in a number of studies during the last 20 years. Summarzing, a primary prevention by changing the nutrition seems to be possible; chances of success for the secondary prevention - the prophylaxis of the reinfarction - are less well confirmed.
高脂血症的治疗基于一些营养原则。减轻体重和控制能量的持续营养对大多数高甘油三酯血症有显著影响。对于混合型高脂血症以及伴有超重的高胆固醇血症,限制热量的饮食方式也表现出良好的反应性。增加身体活动,即通过影响热量消耗来实现能量平衡的负值,也是快速降低甘油三酯水平的一项极佳措施。限制糖和酒精的摄入可以排除导致甘油三酯浓度升高的特定机制。对于体重正常的原发性高胆固醇血症,可通过减少和/或改变脂肪摄入来达到预期效果。由于不同脂肪含量的饮食方式都可能使胆固醇水平出现类似程度的降低,而且反复不饱和脂肪酸与饱和脂肪酸之间存在一定比例关系,因此可以根据个人营养习惯进行调整。然而,我们自己的研究得出结论,脂肪的总摄入量应低于35千卡%。在过去20年的多项研究中,探讨了通过降低血脂的饮食能否降低冠心病风险。总的来说,通过改变饮食进行一级预防似乎是可行的;二级预防(预防再梗死)的成功几率则不太明确。