Schneider H J, Hesse A, Berg W, Kirsten J, Nickel H
Z Urol Nephrol. 1977 Jun;70(6):419-27.
By chronic intoxication with ethylene glycol or acute intoxication by Na-glyoxalate in the animal experiment a Ca-oxalatenephrolithiasis could be produced. At this model the influence of magnesium, pyridoxine and phosphate was studied. The combination therapy of magnesium and vitamin B6 can completely prevent the formation of Ca-oxalate-microliths in the kidney. The production of a preparation with 200 mg MgO and 10 mg pyridoxine per tablet for the metaphylaxis of oxalate calculi is recommended.
在动物实验中，通过乙二醇慢性中毒或乙二醛酸钠急性中毒可引发草酸钙肾结石。在此模型上研究了镁、吡哆醇和磷酸盐的影响。镁和维生素B6的联合治疗可完全预防肾脏中草酸钙微结石的形成。建议制备一种每片含200毫克氧化镁和10毫克吡哆醇的制剂用于预防草酸盐结石。
