Giusti G, Ruggiero G, Galanti B, Piccinino F, Sagnelli E, Lucchelli P E
Acta Hepatogastroenterol (Stuttg). 1977 Aug;24(4):226-37.
The etiological and clinical aspects of viral hepatitis were evaluated by a retrospective survey of patients hospitalized in 1972, 1973 and 1974 in 12 specialized medical centers scattered throughout Italy. The data refer to 2788 patients suffering from acute viral hepatitis who were hospitalized during the initial 10 days of jaundice. The majority of patients (90%) had not been treated with steroids. For each case, the clinical and biochemical data were recorded, coded, computerized and statistically analyzed. In our patient population viral hepatitis was more frequent among younger patients. We observed a high frequency of HBsAg positive hepatitis (40.7%) which was seldom associated to a history of parenteral exposure and showed an irregular geographical distribution. HBsAg positive hepatitis was similarly distributed between males and females. It was more frequent in patients older than 30 (60%) than in children (18-23%) and younger patients (42%). In our series, the frequency of HBsAg hepatitis found in surgeons (81.8%) and nursing personnel (66.3%), but not in physicians (41.2%), was greater than that of the entire sample due to their exposure to blood.
通过对1972年、1973年和1974年在意大利各地12个专业医疗中心住院患者的回顾性调查，对病毒性肝炎的病因和临床方面进行了评估。数据涉及2788例急性病毒性肝炎患者，他们在黄疸出现后的最初10天内住院。大多数患者（90%）未接受过类固醇治疗。对每例患者的临床和生化数据进行记录、编码、计算机处理并进行统计分析。在我们的患者群体中，病毒性肝炎在年轻患者中更为常见。我们观察到乙肝表面抗原（HBsAg）阳性肝炎的发生率较高（40.7%），这种肝炎很少与非肠道接触史相关，且呈现出不规则的地理分布。HBsAg阳性肝炎在男性和女性中的分布相似。在30岁以上的患者中更为常见（60%），而在儿童（18 - 23%）和年轻患者（42%）中则较少见。在我们的系列研究中，外科医生（81.8%）和护理人员（66.3%）中发现的HBsAg肝炎发生率高于整个样本，而内科医生中（41.2%）则不然，这是由于他们接触血液的缘故。
