Krausz Y, Melamed S, Sandler S G, Eliakim M
Isr J Med Sci. 1977 Jan;13(1):9-14.
The epidemiologic, clinical and laboratory features of 40 adults with acute viral hepatitis type B were compared with those of 40 adults with hepatitis non-B. Overall, the clinical presentations were remarkably similar and the etiology could not be determined in individual cases. An exception to this was that all post-transfusion cases in this series were affected by hepatitis B. Men predominated in both the hepatitis B and non-B groups. There was a tendency to seasonal clustering in summer/autumn in both groups. Hepatitis B patients were significantly older and 59% of them had a history of possible parenteral exposure during the six months preceding admission. On the other hand 76% of patients with hepatitis non-B had no apparent parenteral exposure. Dental treatment, injections and contact with jaundiced patients were recorded in both groups and were therefore of no value in determining the exact etiology in individual cases. Fever was more common in hepatitis non-B, while the onset of the disease was insidious and afebrile in 80% of patients with hepatitis B. As a group, patients with hepatitis B had more extensive liver injury and a more prolonged clinical course, and the only fatality was in this group. Cholestatic features were rare and extrahepatic immune complex disease was extremely uncommon in both hepatitis B and non-B.
对40例成人急性乙型病毒性肝炎患者的流行病学、临床及实验室特征与40例非乙型肝炎成人患者进行了比较。总体而言，临床表现非常相似，个别病例无法确定病因。本系列中所有输血后病例均为乙型肝炎，这是个例外情况。乙型肝炎组和非乙型肝炎组男性均占多数。两组在夏秋季均有季节性聚集倾向。乙型肝炎患者年龄显著偏大，其中59%在入院前6个月内有过可能的经肠外途径暴露史。另一方面，76%的非乙型肝炎患者无明显经肠外途径暴露史。两组均记录有牙科治疗、注射及与黄疸患者接触情况，因此这些因素在确定个别病例的确切病因方面无价值。非乙型肝炎患者发热更为常见，而80%的乙型肝炎患者起病隐匿且无发热。作为一个群体，乙型肝炎患者肝损伤范围更广，临床病程更长，且唯一的死亡病例也在该组。胆汁淤积特征罕见，乙型肝炎和非乙型肝炎患者肝外免疫复合物疾病均极为少见。
