Hill J, Clark A, Scott N A
Department of General and Colorectal Surgery, Manchester Royal Infirmary, England.
J R Soc Med. 1997 Feb;90(2):64-6. doi: 10.1177/014107689709000203.
When requiring surgery, acute exacerbations of Crohn's disease in pregnancy have been reported to carry high maternal and fetal mortality. We report six cases. The women presented at 30, 28, 12, 11, 31 and 25 weeks' gestation and all proved to have intraperitoneal sepsis. In three, the acute symptoms were the first indication of Crohn's disease. All the women recovered and five had healthy babies; the other had a miscarriage when a colonic anastomosis dehisced. In pregnant women with Crohn's disease, the indications for surgery are the same as in non-pregnant patients. For acute manifestations we recommend removal of the source of the sepsis and exteriorization of the bowel ends.
据报道，妊娠期间克罗恩病急性加重需要手术时，母婴死亡率很高。我们报告6例病例。这些女性分别在妊娠30、28、12、11、31和25周就诊，均被证实有腹腔内感染。其中3例，急性症状是克罗恩病的首发表现。所有女性均康复，5例产下健康婴儿；另1例在结肠吻合口裂开后流产。对于患有克罗恩病的孕妇，手术指征与非孕妇相同。对于急性表现，我们建议切除感染源并将肠端外置。
