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Diffusion-weighted magnetic resonance for assessing ileal Crohn's disease activity.用于评估回肠克罗恩病活动度的扩散加权磁共振成像
Inflamm Bowel Dis. 2014 Sep;20(9):1575-83. doi: 10.1097/MIB.0000000000000128.
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Therapy of complicated Crohn's disease during pregnancy--an interdisciplinary challenge.妊娠期复杂性克罗恩病的治疗——一项跨学科挑战。
Int J Colorectal Dis. 2014 Jun;29(6):645-51. doi: 10.1007/s00384-014-1880-4. Epub 2014 May 4.
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Relapses of inflammatory bowel disease during pregnancy: in-hospital management and birth outcomes.妊娠期炎症性肠病复发:住院治疗及分娩结局
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Fecal lactoferrin and calprotectin after ileocolonic resection for Crohn's disease.克罗恩病回结肠切除术后的粪便乳铁蛋白和钙卫蛋白
Dis Colon Rectum. 2007 Jun;50(6):861-9. doi: 10.1007/s10350-007-0225-6.
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[Inflammatory bowel disease and pregnancy: report of 76 cases and review of the literature].[炎症性肠病与妊娠:76例报告及文献复习]
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Initial presentation of Crohn's disease in pregnancy: report of a case.克罗恩病在妊娠期的初次表现:病例报告
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Birth outcomes of women with ulcerative colitis: a nationwide Danish cohort study.溃疡性结肠炎女性的分娩结局:一项丹麦全国队列研究。
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Surgical treatment of acute manifestations of Crohn's disease during pregnancy.孕期克罗恩病急性表现的手术治疗
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Crohn's disease with unusual enterouterine fistula in pregnancy.孕期克罗恩病合并罕见的肠子宫瘘
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孕期因肠梗阻行急诊手术,术中发现回肠克罗恩病(CD)

Emergency surgery for intestinal obstruction revealing ileal Crohn's disease (CD) during pregnancy.

作者信息

Furderer Thomas, Mantion Georges, Heyd Bruno

机构信息

University Hospital Besançon, Besançon, France.

出版信息

BMJ Case Rep. 2015 May 12;2015:bcr2013009468. doi: 10.1136/bcr-2013-009468.

DOI:10.1136/bcr-2013-009468
PMID:25969480
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4434334/
Abstract

Few data are available regarding emergency surgery for Crohn's disease (CD) during pregnancy. A 22-year -old woman, at 26 weeks of pregnancy, was admitted for premature labour, intestinal obstruction and systemic inflammation. Biology and ultrasonography were not helpful; imaging was completed with a CT scan, which confirmed the mechanical ileal obstruction. The intestinal obstruction worsened and led to emergency surgery. An inflammatory stenosis of the terminal ileum with two fistulas was found. An ileal resection and ileostomy were performed. The pathological analysis of the resected specimen confirmed CD. The postoperative course was uneventful. The delivery of a baby with normal weight and status occurred at term (40 weeks of amenorrhoea). There have been only 10 case reports of intestinal complications revealing CD during pregnancy. The delay in diagnosis and adequate treatment led to significant maternal and fetal morbidity and mortality. This case suggests that intestinal surgery for CD is feasible during pregnancy and may be associated with a favourable outcome for the baby as well as for the mother.

摘要

关于孕期克罗恩病(CD)急诊手术的可用数据很少。一名22岁女性,孕26周时因早产、肠梗阻和全身炎症入院。生物学检查和超声检查均无帮助;通过CT扫描完成影像学检查,证实为机械性回肠梗阻。肠梗阻加重并导致急诊手术。发现末端回肠炎性狭窄伴两个瘘管。进行了回肠切除和回肠造口术。切除标本的病理分析证实为CD。术后过程顺利。足月(停经40周)分娩出一名体重和状况正常的婴儿。仅有10例孕期肠道并发症提示CD的病例报告。诊断和充分治疗的延迟导致了严重的母婴发病和死亡。该病例表明,孕期CD肠道手术是可行的,对婴儿和母亲都可能带来良好结局。