Macklon N S, Greer I A, Bowman A W
Department of Obstetrics and Gynaecology, University of Glasgow, UK.
Br J Obstet Gynaecol. 1997 Feb;104(2):191-7. doi: 10.1111/j.1471-0528.1997.tb11043.x.
To investigate gestational and postural changes in diameter and blood flow in the proximal deep leg veins during pregnancy.
A longitudinal, prospective observational study.
The ultrasound department of a teaching maternity hospital.
Twenty-four healthy women with uncomplicated singleton pregnancies.
Real-time and duplex Doppler ultrasound assessments of the vessel diameter, flow velocity and respiratory flow fluctuation in the proximal deep leg veins of women serially measured from the first trimester of pregnancy to six weeks postnatally.
The effects of increasing gestation and the adoption of the left lateral position on the above parameters.
An increase in vessel diameter and a fall in flow velocity with increasing gestation was observed. However, no change in venous flow variation was observed. Delivery had reverse effects. Flow velocity was slower in the left than right legs, but on adoption of the left lateral position an increase in flow velocity and venous flow variation was observed in both legs during pregnancy.
These data are consistent with the observed increase in incidence and pattern of deep venous thrombosis in pregnancy and may aid interpretation of duplex Doppler ultrasound examinations for deep venous thrombosis in pregnancy. Postural changes should be part of this evaluation. The gravid uterus may not be the sole cause for postural changes in deep venous flow velocity.
研究孕期小腿近端深静脉直径和血流的妊娠及体位变化。
一项纵向、前瞻性观察性研究。
一家教学妇产医院的超声科。
24例单胎妊娠且无并发症的健康女性。
对研究对象从妊娠早期至产后6周进行连续测量，采用实时和双功多普勒超声评估其小腿近端深静脉的血管直径、流速和呼吸血流波动。
妊娠进展及左侧卧位对上述参数的影响。
观察到随着孕周增加，血管直径增大，流速下降。然而，静脉血流变化未见改变。分娩产生相反的影响。左侧腿的流速比右侧慢，但在孕期采取左侧卧位时，双腿的流速和静脉血流变化均增加。
这些数据与孕期深静脉血栓形成发生率及模式的观察结果一致，可能有助于解释孕期深静脉血栓形成的双功多普勒超声检查结果。体位变化应作为该评估的一部分。妊娠子宫可能不是深静脉流速体位变化的唯一原因。
